DermWave™ Pro
revolutionises RF beauty treatments
through VolumetriQ
VolumetriQ offers a non-invasive solution to improve skin health. At its core, it is an RF-based system that directs thermal energy into different layers of the skin with precision and efficiency. This stimulates the natural production of collagen and elastin, the main proteins responsible for the skin’s elasticity and firmness.
VolumetriQ’s benefit lies in its specialized ability to tailor energy delivery to the specific needs and conditions of each individual skin. Using RF technology, VolumetriQ provides an accurate and deep therapy that tightens the skin and restores its volume and contours.

On Top
The ideal pre-treatment
DermWave™ Pro is also specifically designed to increase the permeability of the skin barrier. Active ingredients, creams and serums penetrate the skin better, as if by magic.
Newly designed handpieces for face and body with special circular loop technology, also used in Elon Musk’s TESLA, ensure 100% area effect without side effects.
Scientifically based treatment protocols and the preset DermWave™ Pro interface with all treatment parameters give the practitioner maximum safety.

Knowledge
Hydroporation
Hydroporation
Hydroporation safely hydroporates complex JetPeel™ Original JetCare™ actives across the barrier and aquaporins deep into the epidermis.
DermWave™ Pro fluidises the barrier and makes it more permeable to the active ingredients.
The collimated treatment aerosol jet of the JetPeel™ safely delivers original JetCare™ active ingredients and moisture in high concentrations into deep skin layers.
and moisture are safely transported in high concentration into deep skin layers and are resiliently deposited between collagenous connective tissue.
There, a depot is formed and the active ingredients are released over a longer period of time.
Compared to a JetPeel™ treatment alone, the combination with DermWave™ Pro
achieves up to 30% faster treatment results.
In addition, radio waves simulate a burn on the skin and heat shock proteins are released.
heat shock proteins are synthesised for rapid skin regeneration.
The water content of the epidermis regulates the elasticity and resilience of the skin.
Water is bound in the hydrophobic environment of the stratum corneum by the substances of the natural moisturising factor (NMF), such as glycerol, urea, amino acids and peptides.
such as glycerin, urea, amino acids and peptides.
The specific lipid composition is of decisive importance for the protective function of the skin barrier. In the different skin layers, the lipids are modified by enzymes.
Water and an acidic pH value in the epidermis are necessary prerequisites for sufficient enzyme activity.
The intact stratum corneum represents an insurmountable barrier for water-soluble substances.
Numerous apparative procedures have been developed to transport substances through the protective barrier.
Sound waves (ultrasound) cause the liquid lipid bilayer to vibrate and thus change the consistency and permeability of the membrane.
Electromagnetic waves (radio frequency, microwaves, light energy) heat the lipid layer and fluidise the protective membrane (butter is liquefied when heated).
By abrading the barrier layer (microdermabrasion), active ingredients penetrate better into deep skin layers, but the protective function is lost and the skin is massively damaged.
The skin – the unknown being…
The skin – the unknown being…
At approximately two square metres, the skin is the largest organ in the human body.
The outer layer of skin, the epidermis, is a dynamic system of continuous proliferation and differentiation.
The most important function of the skin, apart from its many other functions (temperature regulation, sensory organ, protection against pollutants and mechanical influences) is the hydration barrier, which prevents the skin and the organism from drying out, and
maintaining the osmotic balance of internal tissues.
These functions are performed by the stratum corneum, the outermost layers of the epidermis.
In contact with the environment, horny cells are permanently worn away and corresponding keratinised keratinocytes are reproduced in the stratum basale.
This regenerative process normally takes about 20 days and is prolonged in the course of life,
whereby the water-binding capacity of the horny layer in particular decreases.
The skin loses elasticity, becomes dry and cracked and barrier damage occurs.
This makes the skin permeable to the penetration of microorganisms, pollutants, toxins and allergens. Epidermal lipids are formed in insufficient quantity and composition.
The consequences are increased permeability of the horny layer and loss of hygroscopic substances and water.
Water is of crucial importance for the function of the skin.
Water is a transport medium and necessary for all physiological functions in the different skin layers. The enzymes that are effective there can only fulfil their functions if there is sufficient hydration. The correct pH value is a prerequisite for sufficient enzyme activities.
Water transport through cell membranes is a fundamental process of life.
Dadurch wird die Haut durchlässig für das Eindringen von Mikroorganismen, Schadstoffen, Toxinen und Allergenen. Epidermale Lipide werden in ungenügender Menge und Zusammensetzung gebildet. Die Folgen sind erhöhte Durchlässigkeit der Hornschicht und Verlust an hygroskopischen Substanzen und Wasser.
Wasser ist für die Funktion der Haut von entscheidender Bedeutung.
Wasser ist ein Transportmedium und notwendig für alle physiologischen Funktionen in den verschiedenen Hautschichten. Die dort wirksamen Enzyme können ihre Funktionen nur bei einer ausreichenden Hydratation erfüllen. Der richtige pH-Wert ist dabei eine Voraussetzung für ausreichende Enzymaktivitäten. Wassertransport durch Zellmembranen ist ein fundamentaler Prozess des Lebens.
Aquaporine
Aquaporins are integral membrane proteins
All living organisms regulate the inflow and outflow of water to the cells so that the function, shape and size of the cells are maintained.
Special proteins called “aquaporins” are responsible for this.
Aquaporins (AQP) are water channels that can be regulated externally to control the flow of water into and out of the cell.
All known aquaporins have a similar structure and amino acid sequence.
AQP1 consists of a chain of 268 amino acids. This forms six helices that span the membrane (integral membrane protein).
At the end of the helix is a characteristic structure consisting of three amino acids (aspara-gin-proline-alanine), which contributes significantly to the selectivity of the water channel. [Farage MA. Textbook of Aging Skin, Springer-Verlag Berlin Heidelberg 2010].
Aquaporins have also been detected in the lipid membrane of the skin.
The lipid layer of the stratum corneum is water-repellent (hydrophobic) in its interior.
Therefore, its conductivity for water molecules is very low.

Fig 1: Aquaporins as integral structural proteins in the lipid membrane. [de Groot, B et al: Water Permeation Across Biological Membranes: Mechanism and Dynamics of Aquaporin-1 and GlpF, Science (2001), 294, 2353-2357]
For water to reach deep skin layers via the lipid layer, free water must either be conducted through specific channels or bound to hydrophilic substances along the desmo-some bridges into the epidermis.
The water content of the epidermis is regulated by the substances of the natural moisturising factor (NMF). Barrier damage leads to increased water loss (TEWL = transepidermal water loss) and dry and sensitive skin. LANDSBERG EDELWEISS® series and skinbetter science® products repair barrier damage and improve skin moisture and elasticity.
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