
DermWave™ was specially developed and designed to increase the permeability of the skin barrier. Active ingredients, creams and serums penetrate the skin better as if by magic.
Newly designed handpieces for face and body with a special ceramic surface from space travel ensure the best treatment results with maximum safety for your treatment customers. Ceramic does not conduct heat and is e.g. used in the heat protection shield of the ISS in space. However, the special homogenized radio waves penetrate the ceramic unhindered, so that only the skin barrier is explicitly heated up to the desired temperature.
Scientifically based treatment protocols and the preset DermWave™ interface with all treatment parameters give the practitioner maximum security.
Ceramic RF + Hydroporation = fountain of youth and rejuvenating care for your skin!
It is a new, scientifically founded treatment method for deep skin rejuvenation and sustainable and holistic skin care. The protective barrier is renewed and repaired, wrinkles are smoothed, pigment disorders are balanced and the skin is provided with a freshness kick from high-quality peptides, antioxidants, vital substances and anti-aging ingredients right down to the regeneration layer (stratum basale).
With radio waves (DermWave™) the protective barrier is made more permeable for a short time and by heating the skin regeneration processes are initiated, collagen stimulated, elastin is shortened and wrinkles are smoothed. Thanks to the now permeable skin barrier, highly effective vital substances with the collimated jet of JetPeel™ technology are transported into deep skin layers without contact, needles and painlessly and form a depot in the different skin layers for a long-lasting effect. The skin barrier is then strengthened and repaired by skin-identical lipids, vital substances and membrane creams (Edelweiss, Skinbetter) and thus prepared for sustainable rejuvenation.
The skin – the unknown being…
At around two square meters, the skin is the largest human organ. The outer layer of skin, the epidermis, represents a dynamic system of continuous proliferation and differentiation. The most important function of the skin, in addition to its many other functions (temperature regulation, sensory organ, protection against pollutants and mechanical influences), is the hydration barrier that prevents the skin from drying out and of the organism and maintains the osmotic balance of internal tissues.
These functions are performed by the stratum corneum, the outermost layers of the epidermis. In contact with the environment, horn cells are permanently worn out and corresponding keratinized keratinocytes are reproduced in stratum basale. This regenerative process usually lasts about 20 days and increases over the course of a lifetime, in particular the water retention capacity of the corneal layer decreases. The skin loses elasticity, becomes dry and cracked and barrier damage occurs.
This makes the skin permeable to pollutants, the penetration of microorganisms, toxins and allergens. Epidermal lipids are formed in insufficient quantity and composition. The consequences are increased permeability of the horny layer and loss of hygroscopic substances and water.
Water is of crucial importance for the function of the skin. Water is a transport medium and necessary for all physiological functions in the various skin layers. The enzymes that work there can only fulfill their functions if they are sufficiently hydrated. The correct pH value is a prerequisite for sufficient enzyme activity. Water transport through cell membranes is a fundamental process of life.
DermWave™ Equipment – handpieces, ceramic heads, Samsung TouchPad






Aquaporins are integral membrane proteins
Aquaporins
All living organisms regulate the inflow and outflow of water to the cells so that the function, shape and size of the cells are preserved. Special proteins, called “aquaporins”, are responsible for this. Aquaporins (AQP) are water channels that can be controlled from the outside to control the flow of water into and out of the cell.
All known aquaporins have a similar structure and amino acid sequence. The AQP1 consists of a chain of 268 amino acids. This forms six helices that span the membrane (integral membrane protein). At the end of the helix there is a characteristic structure consisting of three amino acids (asparagine-proline-alanine), which contributes significantly to the selectivity of the water channel. [Farage MA. Textbook of Aging Skin, Springer-Verlag Berlin Heidelberg 2010]. Aquaporins were also detected in the lipid membrane of the skin. The inside of the lipid layer of the stratum corneum is water-repellent (hydrophobic). Therefore, their conductivity for water molecules is very low.

Fig. 1: Aquaporins as integral structural proteins in the lipid membrane. [de Groot, B et al: Water Permeation Across Biological Membranes: Mechanism and Dynamics of Aquaporin-1 and GlpF, Science (2001), 294, 2353-2357]
In order for water to reach deep layers of the skin through the lipid layer, free water must either be channeled through specific channels or bound to hydrophilic substances and transported into the epidermis along the desmosome bridges. The water content of the epidermis is regulated by the substances of the natural moisture factor (NMF). Barrier damage results in increased water loss (TEWL = transepidermal water loss) and dry and sensitive skin. LANDSBERG Edelweiss series and Skinbetter products repair barrier damage and improve skin moisture and elasticity of the skin.
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